The museum houses antiquities from the island of Kephalonia, ranging from the prehistoric to the Roman periods. It also contains a remarkable collection of Mycenaean finds.
The old museum was destroyed by the earthquakes of 1953 and the new one was built in 1960.
The most important exhibits are: Mycenaean kylix. Conical, footed cup, decorated with cross-hatched triangles. It was found at the Mycenaean cemetery of Lakkithra
and dates from the 12th century BC. Bronze fibula. The bow is shaped as a row of eight-figured loops. It was found at the Mycenaean cemetery of Diakata and dates from the 12th century BC. Large, two-handled krater. It has a low foot and is decorated with panelled motives between the handles. It was found at the cemetery of Diakata and dates from the 12th century BC. Gold necklace from the Mycenaean cemetery at Lakkithra. It is made of pairs of gold spirals and was found intentionally twisted. Dated to the 12th century BC.